Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma.

doi:10.1002/ijc.29863

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma.

International journal of cancer - 1 Mar 2016

Ek Weronica E, Lagergren Katarina, Cook Michael, Wu Anna H, Abnet Christian C, Levine David, Chow Wong-Ho, Bernstein Leslie, Risch Harvey A, Shaheen Nicholas J, Bird Nigel C, Corley Douglas A, Hardie Laura J, Fitzgerald Rebecca C, Gammon Marilie D, Romero Yvonne, Liu Geoffrey, Ye Weimin, Vaughan Thomas L, MacGregor Stuart, Whiteman David C, Westberg Lars, Lagergren Jesper

Abstract excerpt

The strong male predominance in Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) remains inadequately explained, but sex hormones might be involved. We hypothesized that single nucleotide polymorphisms (SNPs) in the androgen pathway influence risk of developing BE and EAC. This genetic-epidemiological analysis included 14 studies from Australia, Europe and North America. Polymorphisms in 16 genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged

Share to Barrett Esophagus

Share to Esophageal Neoplasms

Share to Jumonji Domain-Containing Histone Demethylases

Share to Oxidoreductases, N-Demethylating

Share to Risk

Share to Steroid 17-alpha-Hydroxylase

Source

Open in PubMed Open full text

Identifiers

PMID: 26414697
DOI: 10.1002/ijc.29863
PMCID: PMC4715576

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in genes in the androgen pathway and risk of Barrett's esophagus and esophageal adenocarcinoma.PMID 26414697Read ↗

Sex-Specific Genetic Associations for Barrett's Esophagus and Esophageal Adenocarcinoma.Semantic proximity Read ↗

Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma.Semantic proximity Read ↗

Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett's Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium.Semantic proximity Read ↗

Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux.Semantic proximity Read ↗

Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseasesSemantic proximity Read ↗

Germline variation in the insulin-like growth factor pathway and risk of Barrett's esophagus and esophageal adenocarcinoma.Semantic proximity Read ↗

Association of variants in estrogen-related pathway genes with prostate cancer risk.Semantic proximity Read ↗

A Large-scale genetic association study of esophageal adenocarcinoma risk.Semantic proximity Read ↗

Genome-Wide Analysis of Sex Disparities in the Genetic Architecture of Lung and Colorectal Cancers.Semantic proximity Read ↗

Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma.Semantic proximity Read ↗

Profiling genetic variation along the androgen biosynthesis and metabolism pathways implicates several single nucleotide polymorphisms and their combinations as prostate cancer risk factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.