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Article

A survey of disease connections for CD4+ T cell master genes and their directly linked genes.

Computational biology and chemistry - 1 Dec 2015

Li Wentian, Espinal-Enríquez Jesús, Simpfendorfer Kim R, Hernández-Lemus Enrique

Abstract excerpt

Genome-wide association studies and other genetic analyses have identified a large number of genes and variants implicating a variety of disease etiological mechanisms. It is imperative for the study of human diseases to put these genetic findings into a coherent functional context. Here we use system biology tools to examine disease connections of five master genes for CD4+ T cell subtypes (TBX21, GATA3, RORC,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26411796
DOI: 10.1016/j.compbiolchem.2015.08.009

Genes

BCL6
FOXP3
GATA3
RORC
TBX21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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