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Article

Pathway Maps of Orphan and Complex Diseases Using an Integrative Computational Approach.

BioMed research international - 1 Jan 2020

Ghedira Kais, Kouidhi Soumaya, Hamdi Yosr, Othman Houcemeddine, Kechaou Sonia, Znaidi Sadri, Haïtham Sghaier, Rabhi Imen

Abstract excerpt

Orphan diseases (ODs) are progressive genetic disorders, which affect a small number of people. The principal fundamental aspects related to these diseases include insufficient knowledge of mechanisms involved in the physiopathology necessary to access correct diagnosis and to develop appropriate healthcare. Unlike ODs, complex diseases (CDs) have been widely studied due to their high incidence and prevalence...

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Identifiers

PMID: 33376724
DOI: 10.1155/2020/4280467
PMCID: PMC7744584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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