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Article

RAD51C mutation screening in high-risk patients from Serbian hereditary breast/ovarian cancer families.

Cancer biomarkers : section A of Disease markers - 1 Jan 2015

Krivokuca Ana, Yanowski Kira, Rakobradovic Jelena, Benitez Javier, Brankovic-Magic Mirjana

Abstract excerpt

BACKGROUND: In 2010 an important finding was published showing that heterozygous mutations in RAD51C were highly penetrant and were able to confer an increased risk for breast and ovarian cancers. The role of possible third high penetrance breast cancer susceptibility gene was assigned to RAD51C. OBJECTIVE: Because of its rising importance in breast cancer development and the lack of information about RAD51C in...

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Source

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Identifiers

PMID: 26406419
DOI: 10.3233/CBM-150519
PMCID: PMC12965469

Genes

RAD51C
MAF
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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RAD51C mutation screening in high-risk patients from Serbian hereditary breast/ovarian cancer families.PMID 26406419Read ↗

Evaluation of RAD51C as cancer susceptibility gene in a large breast-ovarian cancer patient population referred for genetic testing.Semantic proximity Read ↗

Deleterious RAD51C germline mutations rarely predispose to breast and ovarian cancer in Pakistan.Semantic proximity Read ↗

Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families.Semantic proximity Read ↗

Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer.Semantic proximity Read ↗

RAD51C germline mutations in breast and ovarian cancer cases from high-risk families.Semantic proximity Read ↗

Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility.Semantic proximity Read ↗

Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patientsSemantic proximity Read ↗

Germline RAD51C mutations in ovarian cancer susceptibility.Semantic proximity Read ↗

Mutation screening of RAD51C in high-risk breast and ovarian cancer families.Semantic proximity Read ↗

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene.Semantic proximity Read ↗

Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients.Semantic proximity Read ↗

Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic.Semantic proximity Read ↗

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