Article
APOE-ɛ4 Carrier Status and Donepezil Response in Patients with Alzheimer's Disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2015
Waring Jeffrey F, Tang Qi, Robieson Weining Z, King David P, Das Ujjwal, Dubow Jordan, Dutta Sandeep, Marek Gerard J, Gault Laura M
Abstract excerpt
BACKGROUND: Previous studies have investigated associations between apolipoprotein E (APOE)-ɛ4 allele status and acetylcholinesterase inhibitor treatment response in patients with Alzheimer's disease. The ability to draw definitive conclusions regarding the effect of APOE-ɛ4 genotype on treatment response has been hindered by inconsistent results among studies and methodological limitations that restrict...
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