Article
Effect of ApoE genotype on response to donepezil in patients with Alzheimer's disease.
Dementia and geriatric cognitive disorders - 1 Jan 2008
Choi Seong Hye, Kim Sang Yun, Na Hae Ri, Kim Byung-Kun, Yang Dong Won, Kwon Jay C, Park Mee Young
Abstract excerpt
BACKGROUND/AIMS: The possible influence of apolipoprotein E (ApoE) genotype on the response to acetylcholinesterase inhibitor therapy in patients with Alzheimer's disease (AD) remains a matter of controversy. In order to address this issue, we investigated the effects of ApoE genotype on the clinical response to donepezil in patients with mild to moderate AD. METHODS: An open study was carried out in 51 patients...
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