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Impact of apolipoprotein E genotypes on vitamin E and memantine treatment outcomes in Alzheimer's disease

1 Jan 2018

Abstract excerpt

INTRODUCTION: Because apolipoprotein E (APOE) genotypes are known risk factors for Alzheimer's disease (AD), they have been measured in clinical trial participants to determine their effect on treatment outcome. METHODS: We determined APOE genotypes in a subset of subjects (N = 415) who participated in a randomized controlled trial of vitamin E and memantine in 613 veterans with mild-to-moderate AD. RESULTS:...

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PMID: 30175228
DOI: 10.1016/j.trci.2018.06.001

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