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Article

Melatonin Attenuates Memory Impairment, Amyloid-β Accumulation, and Neurodegeneration in a Rat Model of Sporadic Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Rudnitskaya Ekaterina A, Muraleva Natalia A, Maksimova Kseniya Yi, Kiseleva Elena, Kolosova Nataliya G, Stefanova Natalia A

Abstract excerpt

Melatonin is a multifunctional molecule and plays a crucial role in the regulation of circadian rhythms. The role of melatonin in the protection of the central nervous system is well documented. Therefore, melatonin was proposed as a possible therapeutic agent for reducing the severity of Alzheimer's disease (AD), a progressive neurodegenerative disease characterized by cognitive decline and memory dysfunction....

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PMID: 26402759
DOI: 10.3233/JAD-150161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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