Article
Event-related potential markers of brain changes in preclinical familial Alzheimer disease.
Neurology - 2 Aug 2011
Quiroz Y T, Ally B A, Celone K, McKeever J, Ruiz-Rizzo A L, Lopera F, Stern C E, Budson A E
Abstract excerpt
OBJECTIVES: Event-related potentials (ERPs) can reflect differences in brain electrophysiology underlying cognitive functions in brain disorders such as dementia and mild cognitive impairment. To identify individuals at risk for Alzheimer disease (AD) we used high-density ERPs to examine brain physiology in young presymptomatic individuals (average age 34.2 years) who carry the E280A mutation in the presenilin-1...
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