Article
Does toll-like receptor-3 (TLR-3) have any role in Indian AMD phenotype?
Molecular and cellular biochemistry - 1 Aug 2014
Sharma Neel Kamal, Sharma Kaushal, Gupta Amod, Prabhakar Sudesh, Singh Ramandeep, Gupta Pawan Kumar, Anand Akshay
Abstract excerpt
Age-related macular degeneration (AMD) is a devastating disease that results in irreversible central vision loss. TLRs signaling pathway has been found to play an important role in AMD pathogenesis as evidenced by several studies. The objective of the study was to determine the single nucleotide polymorphism (SNP) changes in TLR3 in North Indian AMD patients. We recruited 176 patients comprising 115 AMD patients...
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