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Article

Associations of TLR4 and IL-8 genes polymorphisms with age-related macular degeneration (AMD): a systematic review and meta-analysis.

Ophthalmic genetics - 1 Dec 2021

Roshanipour Nasrin, Shahriyari Elham, Ghaffari Laleh Maryam, Vahedi Leila, Mirjand Gerami Sousan, Khamaneh Amin

Abstract excerpt

BACKGROUND: The results of different studies have indicated the possible associations of TLR4 and IL-8 genes polymorphisms with Age-related Macular Degeneration (AMD). A meta-analysis study was designed to evaluate the possible associations of TLR4 (rs4986790/c.896A>G and rs4986791/ c.1196 C > T) and IL-8 (rs4073/c.251A>T and rs2227306/c.781 C > T) genes polymorphisms with AMD. METHOD: A systematic literature...

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Identifiers

PMID: 34287094
DOI: 10.1080/13816810.2021.1955274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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