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Article

The DNA replication factor RFC1 is required for interference-sensitive meiotic crossovers in Arabidopsis thaliana.

PLoS genetics - 1 Jan 2012

Wang Yingxiang, Cheng Zhihao, Huang Jiyue, Shi Qian, Hong Yue, Copenhaver Gregory P, Gong Zhizhong, Ma Hong

Abstract excerpt

During meiotic recombination, induced double-strand breaks (DSBs) are processed into crossovers (COs) and non-COs (NCO); the former are required for proper chromosome segregation and fertility. DNA synthesis is essential in current models of meiotic recombination pathways and includes only leading strand DNA synthesis, but few genes crucial for DNA synthesis have been tested genetically for their functions in...

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Share to Chromosome Segregation
Share to Chromosomes, Plant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crossing Over, Genetic

Share to DNA Breaks, Double-Stranded

Share to DNA Helicases

Share to Homologous Recombination

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Share to Replication Protein C

Source

Open in PubMed Open full text

Identifiers

PMID: 23144629
DOI: 10.1371/journal.pgen.1003039
PMCID: PMC3493451

Genes

RFC1
MUS81
MSH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The DNA replication factor RFC1 is required for interference-sensitive meiotic crossovers in Arabidopsis thaliana.PMID 23144629Read ↗

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AAA-ATPase FIDGETIN-LIKE 1 and Helicase FANCM Antagonize Meiotic Crossovers by Distinct Mechanisms.Semantic proximity Read ↗

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