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Article

miR‐34a is an intracellular and exosomal predictive biomarker for response to docetaxel with clinical relevance to prostate cancer progression

22 Jul 2014

Abstract excerpt

BACKGROUND: Docetaxel-resistance limits successful treatment of castration resistant prostate cancer. We previously demonstrated that extracellular vesicles (exosomes) may play a role in regulating docetaxel resistance. Here, we investigated intracellular and extracellular (exosomal) miRNAs related to docetaxel resistance. METHODS: Following global miRNA profiling of cell line models of docetaxel-resistance and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25053345
DOI: 10.1002/pros.22848

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