Article
Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses.
PLoS medicine - 1 Sept 2016
Khankari Nikhil K, Shu Xiao-Ou, Wen Wanqing, Kraft Peter, Lindström Sara, Peters Ulrike, Schildkraut Joellen, Schumacher Fredrick, Bofetta Paolo, Risch Angela, Bickeböller Heike, Amos Christopher I, Easton Douglas, Eeles Rosalind A, Gruber Stephen B, Haiman Christopher A, Hunter David J, Chanock Stephen J, Pierce Brandon L, Zheng Wei
Abstract excerpt
BACKGROUND: Observational studies examining associations between adult height and risk of colorectal, prostate, and lung cancers have generated mixed results. We conducted meta-analyses using data from prospective cohort studies and further carried out Mendelian randomization analyses, using height-associated genetic variants identified in a genome-wide association study (GWAS), to evaluate the association of...
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