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Article

Urinary Tract Cancer in Lynch Syndrome; Increased Risk in Carriers of MSH2 Mutations.

Urology - 1 Dec 2015

Joost Patrick, Therkildsen Christina, Dominguez-Valentin Mev, Jönsson Mats, Nilbert Mef

Abstract excerpt

OBJECTIVE: To evaluate the risk of urothelial cancer in the upper urinary tract and the bladder, determine the contribution from the different mismatch-repair genes, and define clinical characteristics of urothelial cancer in Lynch syndrome. MATERIALS AND METHODS: The national hereditary nonpolyposis colorectal cancer registry was used to identify all 288 Lynch syndrome families in Denmark. Urothelial cancers...

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Share to DNA Repair Enzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mismatch Repair Endonuclease PMS2

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Share to Neoplasms, Multiple Primary

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Source

Identifiers

PMID: 26385421
DOI: 10.1016/j.urology.2015.08.018

Genes

MSH2
MLH1
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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