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Article

Uroepithelial and kidney carcinoma in Lynch syndrome.

Familial cancer - 1 Sept 2012

Aarnio Markku, Säily Matti, Juhola Matti, Gylling Annette, Peltomäki Päivi, Järvinen Heikki J, Mecklin Jukka-Pekka

Abstract excerpt

Increased risk for urological tumors has been observed in mutation carriers with Lynch syndrome (LS). In this study, we evaluated the clinical features of uroepithelial (bladder and ureter) and kidney cancers in 974 Finnish mutation carriers. Altogether 30 patients had a total of 34 urological tumors: 12 ureter, 12 bladder, and 10 kidney cancers. Urological tumor was the only tumor in 9 (30 %) patients, and...

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Source

Identifiers

PMID: 22476430
DOI: 10.1007/s10689-012-9526-6

Genes

MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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