Article
Greenlandic Inuit show genetic signatures of diet and climate adaptation.
Science (New York, N.Y.) - 18 Sept 2015
Fumagalli Matteo, Moltke Ida, Grarup Niels, Racimo Fernando, Bjerregaard Peter, Jørgensen Marit E, Korneliussen Thorfinn S, Gerbault Pascale, Skotte Line, Linneberg Allan, Christensen Cramer, Brandslund Ivan, Jørgensen Torben, Huerta-Sánchez Emilia, Schmidt Erik B, Pedersen Oluf, Hansen Torben, Albrechtsen Anders, Nielsen Rasmus
Abstract excerpt
The indigenous people of Greenland, the Inuit, have lived for a long time in the extreme conditions of the Arctic, including low annual temperatures, and with a specialized diet rich in protein and fatty acids, particularly omega-3 polyunsaturated fatty acids (PUFAs). A scan of Inuit genomes for signatures of adaptation revealed signals at several loci, with the strongest signal located in a cluster of fatty acid...
Topics
- Acclimatization
- Alleles
- Arctic Regions
- Body Height
- Body Weight
- Chromosomes, Human, Pair 11
- Climate
- Diet, High-Fat
- Fatty Acids, Omega-3