Article
Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans.
Genome medicine - 23 May 2024
Lin Long, Andersen Mette K, Stæger Frederik Filip, Li Zilong, Hanghøj Kristian, Linneberg Allan, Grarup Niels, Jørgensen Marit Eika, Hansen Torben, Moltke Ida, Albrechtsen Anders
Abstract excerpt
BACKGROUND: Disease prevalence and mean phenotype values differ between many populations, including Inuit and Europeans. Whether these differences are partly explained by genetic differences or solely due to differences in environmental exposures is still unknown, because estimates of the genetic contribution to these means, which we will here refer to as mean genotypic values, are easily confounded, and because...
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