Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet.

European journal of human genetics : EJHG - 1 Nov 2020

Senftleber Ninna, Jørgensen Marit Eika, Jørsboe Emil, Imamura Fumiaki, Forouhi Nita Gandhi, Larsen Christina Lytken, Bjerregaard Peter, Hansen Torben, Albrechtsen Anders

Abstract excerpt

Several recent studies have found signs of recent selection on the carnitine palmitoyl-transferase 1A (CPT1A) gene in the ancestors of Arctic populations likely as a result of their traditional diet. CPT1A is involved in fatty acid transportation and is known to affect circulating fatty acid profiles in Inuit as does the unique traditional diet rich in marine animals. We aimed to assess which fatty acids may have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acclimatization
Share to Blood Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carnitine O-Palmitoyltransferase

Share to Fatty Acids

Share to Polymorphism, Single Nucleotide

Share to Selection, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 32561900
DOI: 10.1038/s41431-020-0674-0
PMCID: PMC7576585

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet.PMID 32561900Read ↗

CPT1A Missense Mutation Associated With Fatty Acid Metabolism and Reduced Height in Greenlanders.Semantic proximity Read ↗

Inuit metabolism revisited: what drove the selective sweep of CPT1a L479?Semantic proximity Read ↗

Greenlandic Inuit show genetic signatures of diet and climate adaptation.Semantic proximity Read ↗

Increased missense mutation burden of Fatty Acid metabolism related genes in nunavik inuit population.Semantic proximity Read ↗

Genetic polymorphisms in carnitine palmitoyltransferase 1A gene are associated with variation in body composition and fasting lipid traits in Yup'ik Eskimos.Semantic proximity Read ↗

Genetics of metabolic traits in Greenlanders: lessons from an isolated populationSemantic proximity Read ↗

Carnitine palmitoyltransferase-1A deficiency: a look at classic and arctic variants.Semantic proximity Read ↗

Carnitine palmitoyltransferase IA polymorphism P479L is common in Greenland Inuit and is associated with elevated plasma apolipoprotein A-I.Semantic proximity Read ↗

Diet and physical activity in Greenland: genetic interactions and associations with obesity and diabetes.Semantic proximity Read ↗

The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders.Semantic proximity Read ↗

Hypertriglyceridemic-waist phenotype and glucose intolerance among Canadian Inuit: the International Polar Year Inuit Health Survey for Adults 2007-2008.Semantic proximity Read ↗

The effect of traditional diet on glucose homoeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: a randomised crossover study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.