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Genomic prediction using imputed whole-genome sequence data in Holstein Friesian cattle.

Genetics, selection, evolution : GSE - 17 Sept 2015

van Binsbergen Rianne, Calus Mario P L, Bink Marco C A M, van Eeuwijk Fred A, Schrooten Chris, Veerkamp Roel F

Abstract excerpt

BACKGROUND: In contrast to currently used single nucleotide polymorphism (SNP) panels, the use of whole-genome sequence data is expected to enable the direct estimation of the effects of causal mutations on a given trait. This could lead to higher reliabilities of genomic predictions compared to those based on SNP genotypes. Also, at each generation of selection, recombination events between a SNP and a mutation...

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Identifiers

PMID: 26381777
DOI: 10.1186/s12711-015-0149-x
PMCID: PMC4574568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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