Utility of whole-genome sequence data for across-breed genomic prediction.

doi:10.1186/s12711-018-0396-8

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Article

Utility of whole-genome sequence data for across-breed genomic prediction.

Genetics, selection, evolution : GSE - 18 May 2018

Raymond Biaty, Bouwman Aniek C, Schrooten Chris, Houwing-Duistermaat Jeanine, Veerkamp Roel F

Abstract excerpt

BACKGROUND: Genomic prediction (GP) across breeds has so far resulted in low accuracies of the predicted genomic breeding values. Our objective was to evaluate whether using whole-genome sequence (WGS) instead of low-density markers can improve GP across breeds, especially when markers are pre-selected from a genome-wide association study (GWAS), and to test our hypothesis that many non-causal markers in WGS data...

Topics

Animals
Biometry
Breeding
Cattle
Computational Biology
Genetic Variation
Genome-Wide Association Study
Male
Models, Genetic
Pedigree
Polymorphism, Single Nucleotide
Quantitative Trait Loci

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Identifiers

PMID: 29776327
DOI: 10.1186/s12711-018-0396-8
PMCID: PMC5960108

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