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Article

Accuracy of prediction of simulated polygenic phenotypes and their underlying quantitative trait loci genotypes using real or imputed whole-genome markers in cattle.

Genetics, selection, evolution : GSE - 23 Dec 2015

Hassani Saeed, Saatchi Mahdi, Fernando Rohan L, Garrick Dorian J

Abstract excerpt

BACKGROUND: More accurate genomic predictions are expected when the effects of QTL (quantitative trait loci) are predicted from markers in close physical proximity to the QTL. The objective of this study was to quantify to what extent whole-genome methods using 50 K or imputed 770 K SNPs (single nucleotide polymorphisms) could predict single or multiple QTL genotypes based on SNPs in close proximity to those QTL....

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PMID: 26698091
DOI: 10.1186/s12711-015-0179-4
PMCID: PMC4689055

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