Article
Phenotypic and gene expression modification with normal brain aging in GFAP-positive astrocytes and neural stem cells.
Aging cell - 1 Jun 2011
Bernal Giovanna M, Peterson Daniel A
Abstract excerpt
Astrocytes secrete growth factors that are both neuroprotective and supportive for the local environment. Identified by glial fibrillary acidic protein (GFAP) expression, astrocytes exhibit heterogeneity in morphology and in the expression of phenotypic markers and growth factors throughout different adult brain regions. In adult neurogenic niches, astrocytes secrete vascular endothelial growth factor (VEGF) and...
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