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Article

Genetic Diversity and Natural Selection of the Plasmodium knowlesi Circumsporozoite Protein Nonrepeat Regions.

PloS one - 1 Jan 2015

Fong Mun Yik, Ahmed Md Atique, Wong Shen Siang, Lau Yee Ling, Sitam Frankie

Abstract excerpt

BACKGROUND: Plasmodium knowlesi is a simian malaria parasite that has been identified to cause malaria in humans. To date, several thousand cases of human knowlesi malaria have been reported around Southeast Asia. Thus far, there is no detailed study on genetic diversity and natural selection of P. knowlesi circumsporozoite protein (CSP), a prominent surface antigen on the sporozoite of the parasite. In the...

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PMID: 26379157
DOI: 10.1371/journal.pone.0137734
PMCID: PMC4575020

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