Article
Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi.
Proceedings of the National Academy of Sciences of the United States of America - 20 Oct 2015
Assefa Samuel, Lim Caeul, Preston Mark D, Duffy Craig W, Nair Mridul B, Adroub Sabir A, Kadir Khamisah A, Goldberg Jonathan M, Neafsey Daniel E, Divis Paul, Clark Taane G, Duraisingh Manoj T, Conway David J, Pain Arnab, Singh Balbir
Abstract excerpt
Malaria cases caused by the zoonotic parasite Plasmodium knowlesi are being increasingly reported throughout Southeast Asia and in travelers returning from the region. To test for evidence of signatures of selection or unusual population structure in this parasite, we surveyed genome sequence diversity in 48 clinical isolates recently sampled from Malaysian Borneo and in five lines maintained in laboratory rhesus...
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