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Genetic Diversity and Population Genetic Structure Analysis of Plasmodium knowlesi Thrombospondin-Related Apical Merozoite Protein (TRAMP) in Clinical Samples.

Genes - 25 Oct 2022

Ahmed Md Atique, Zaidi Rehan Haider, Deshmukh Gauspasha Yusuf, Saif Ahmed, Alshahrani Mohammed Abdulrahman, Salam Syeda Sabiha, Elfaki Mohammed Mohieldien Abbas, Han Jin-Hee, Patgiri Saurav Jyoti, Quan Fu-Shi

Abstract excerpt

The simian malaria parasite Plasmodium knowlesi causes a high number of zoonotic infections in Malaysia. The thrombospondin-related apical merozoite protein (TRAMP) is an essential ligand for binding to the erythrocyte cell surface, whereby it facilitates the invasion. This study is the first attempt to determine the genetic diversity, phylogeography, natural selection and population structure from 97 full-length...

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Identifiers

PMID: 36360181
DOI: 10.3390/genes13111944
PMCID: PMC9689803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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