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Article

Diversity and natural selection on the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium knowlesi in Malaysia.

Malaria journal - 27 Jul 2018

Ahmed Md Atique, Lau Yee Ling, Quan Fu-Shi

Abstract excerpt

BACKGROUND: Plasmodium knowlesi a parasite of the macaques is currently the most common cause of human malaria in Malaysia. The thrombospondin-related adhesive protein (TRAP) gene is pre-erythrocytic stage antigen. It is a well-characterized vaccine candidate in Plasmodium vivax and Plasmodium falciparum, however, no study has been done in the orthologous gene of P. knowlesi. This study investigates nucleotide...

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Identifiers

PMID: 30053885
DOI: 10.1186/s12936-018-2423-1
PMCID: PMC6062916

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