Article
Genetic diversity of circumsporozoite protein in Plasmodium knowlesi isolates from Malaysian Borneo and Peninsular Malaysia.
Malaria journal - 22 Oct 2020
Chong Eric Tzyy Jiann, Neoh Joveen Wan Fen, Lau Tiek Ying, Lim Yvonne Ai-Lian, Chai Hwa Chia, Chua Kek Heng, Lee Ping-Chin
Abstract excerpt
BACKGROUND: Understanding the genetic diversity of candidate genes for malaria vaccines such as circumsporozoite protein (csp) may enhance the development of vaccines for treating Plasmodium knowlesi. Hence, the aim of this study is to investigate the genetic diversity of non-repeat regions of csp in P. knowlesi from Malaysian Borneo and Peninsular Malaysia. METHODS: A total of 46 csp genes were subjected to...
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