Article
Structural Properties of Gene Promoters Highlight More than Two Phenotypes of Diabetes.
PloS one - 1 Jan 2015
Ionescu-Tîrgovişte Constantin, Gagniuc Paul Aurelian, Guja Cristian
Abstract excerpt
Genome-wide association studies (GWAS) published in the last decade raised the number of loci associated with type 1 (T1D) and type 2 diabetes (T2D) to more than 50 for each of these diabetes phenotypes. The environmental factors seem to play an important role in the expression of these genes, acting through transcription factors that bind to promoters. Using the available databases we examined the promoters of...
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