Article
Linking disease-associated genes to regulatory networks via promoter organization.
Nucleic acids research - 1 Jan 2005
Döhr S, Klingenhoff A, Maier H, Hrabé de Angelis M, Werner T, Schneider R
Abstract excerpt
Pathway- or disease-associated genes may participate in more than one transcriptional co-regulation network. Such gene groups can be readily obtained by literature analysis or by high-throughput techniques such as microarrays or protein-interaction mapping. We developed a strategy that defines regulatory networks by in silico promoter analysis, finding potentially co-regulated subgroups without a priori...
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