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Genes Involved in Type 1 Diabetes: An Update

16 Sept 2013

Abstract excerpt

Type 1 Diabetes (T1D) is a chronic multifactorial disease with a strong genetic component, which, through interactions with specific environmental factors, triggers disease onset. T1D typically manifests in early to mid childhood through the autoimmune destruction of pancreatic β cells resulting in a lack of insulin production. Historically, prior to genome-wide association studies (GWAS), six loci in the genome...

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PMID: 24705215
DOI: 10.3390/genes4030499

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