Article
Independence Day for IgA.
Immunity - 15 Sept 2015
Macpherson Andrew J, McCoy Kathy D
Abstract excerpt
IgA is induced through T-cell-dependent and -independent pathways. In this issue, Bunker et al. (2015) now show that the T-cell-independent pathway is sufficient to coat most small intestinal microbes specifically, and Fransen et al. (2015) find that IgA coating promotes uptake of microbes into Peyer's patches and drives further induction in a positive-feedback loop.
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