Article
Investigation of Rho-Kinase Expressions and Polymorphisms in Mantle Cell Lymphoma Patients.
Turkish journal of haematology : official journal of Turkish Society of Haematology - 5 Jun 2016
Yanardağ Açık Didar, Yılmaz Mehmet, Sarı İbrahim, Öztuzcu Serdar, Sayıner Zeynel A, Subari Salih, Demiryürek Abdullah T
Abstract excerpt
OBJECTIVE: Mantle cell lymphoma (MCL) is a rare but aggressive form of B-cell non-Hodgkin lymphoma characterized by excessive expression of cyclin D1. Intracellular signaling enzyme Rho-kinase (ROCK) can contribute to cellular migration, proliferation, and differentiation, as well as tumor development and metastasis. However, ROCK gene and protein expressions or polymorphisms have never been investigated in MCL...
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