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Article

Molecular Basis of Factor H R1210C Association with Ocular and Renal Diseases.

Journal of the American Society of Nephrology : JASN - 1 May 2016

Recalde Sergio, Tortajada Agustin, Subias Marta, Anter Jaouad, Blasco Miquel, Maranta Ramona, Coco Rosa, Pinto Sheila, Noris Marina, García-Layana Alfredo, Rodríguez de Córdoba Santiago

Abstract excerpt

The complement factor H (FH) mutation R1210C, which was described in association with atypical hemolytic uremic syndrome (aHUS), also confers high risk of age-related macular degeneration (AMD) and associates with C3 glomerulopathy (C3G). To reveal the molecular basis of these associations and to provide insight into what determines the disease phenotype in FH-R1210C carriers, we identified FH-R1210C carriers in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26376859
DOI: 10.1681/ASN.2015050580
PMCID: PMC4849834

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular Basis of Factor H R1210C Association with Ocular and Renal Diseases.PMID 26376859Read ↗

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