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Article

Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome.

Blood - 5 Nov 2009

Abarrategui-Garrido Cynthia, Martínez-Barricarte Rubén, López-Trascasa Margarita, de Córdoba Santiago Rodríguez, Sánchez-Corral Pilar

Abstract excerpt

The factor H-related protein family (CFHR) is a group of minor plasma proteins genetically and structurally related to complement factor H (fH). Notably, deficiency of CFHR1/CFHR3 associates with protection against age-related macular degeneration and with the presence of anti-fH autoantibodies in atypical hemolytic uremic syndrome (aHUS). We have developed a proteomics strategy to analyze the CFHR proteins in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glomerulonephritis, Membranoproliferative

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Source

Identifiers

PMID: 19745068
DOI: 10.1182/blood-2009-05-223834

Genes

CFHR1
CFHR3
CFH
CFHR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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