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Article

Comparative Analyses of Targeted Myeloid Cancer Next-Generation Sequencing Panel in Fresh Blood, Bone Marrow and FFPE Material.

International journal of molecular sciences - 21 Mar 2024

Hobeck Andrea Daniela, Wendt Sophia, Krohn Saskia, Knuebel Gudrun, Bartels Stephan, Schipper Elisa, Junghanss Christian, Murua Escobar Hugo

Abstract excerpt

Next-generation sequencing is a vital tool for personalized diagnostics and therapies in cancer. Despite numerous advantages, the method depends on multiple parameters regarding the sample material, e.g., sample fixation. A panel's ability to ensure balanced pre-amplification of the regions of interest is challenging, especially in targeted sequencing approaches, but of significant importance to its applicability...

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Identifiers

PMID: 38542506
DOI: 10.3390/ijms25063534
PMCID: PMC10970853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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