Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between STAT4 gene polymorphisms and autoimmune thyroid diseases in a Chinese population.

International journal of molecular sciences - 11 Jul 2014

Yan Ni, Meng Shuai, Zhou Jiaozhen, Xu Jian, Muhali Fatuma Said, Jiang Wenjuan, Shi Liangfeng, Shi Xiaohong, Zhang Jinan

Abstract excerpt

The STAT4 gene encodes a transcriptional factor that transmits signals induced by several key cytokines which play important roles in the development of autoimmune diseases. The aim of this study was to explore the association of STAT4 polymorphism with Graves' disease (GD) and Hashimoto's thyroiditis (HT). A total of 1048 autoimmune thyroid diseases (AITDs) patients (693 with GD and 355 with HT) and 909 age- and...

Topics

Join the communities discussing this publication.

Adolescent
Aged
Case-Control Studies
Child
Graves Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hashimoto Disease

Polymorphism, Single Nucleotide

STAT4 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 25019342
DOI: 10.3390/ijms150712280
PMCID: PMC4139844

Genes

STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between STAT4 gene polymorphisms and autoimmune thyroid diseases in a Chinese population.PMID 25019342Read ↗

Association of single-nucleotide polymorphisms in the STAT3 gene with autoimmune thyroid disease in Chinese individuals.Semantic proximity Read ↗

Genetic variants of interleukin-4 gene in autoimmune thyroid diseases: an updated meta-analysis.Semantic proximity Read ↗

Genetic Study in a Large Cohort Supported Different Pathogenesis of Graves' Disease and Hashimoto's Hypothyroidism.Semantic proximity Read ↗

Single nucleotide polymorphisms in the STAT3 gene influence AITD susceptibility, thyroid autoantibody levels, and IL6 and IL17 secretion.Semantic proximity Read ↗

Association of Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Gene Polymorphisms with Autoimmune Thyroid Disease in Children and Adults: Case-Control Study.Semantic proximity Read ↗

Association of single nucleotide polymorphism rs3792876 in SLC22A4 gene with autoimmune thyroid disease in a Chinese Han population.Semantic proximity Read ↗

Polymorphisms of ATG5 Gene Are Associated with Autoimmune Thyroid Diseases, Especially Thyroid Eye Disease.Semantic proximity Read ↗

Unraveling susceptibility genes: A contemporary overview of autoimmune thyroid diseases.Semantic proximity Read ↗

RNASET2 tag SNP but not CCR6 polymorphisms is associated with autoimmune thyroid diseases in the Chinese Han population.Semantic proximity Read ↗

Signal transducer and activator of transcription and the risk of rheumatoid arthritis and thyroid autoimmune disorders.Semantic proximity Read ↗

Polymorphisms of B-lymphocyte-associated genes CD20 and FCRL5 are associated with susceptibility to autoimmune thyroid diseases.Semantic proximity Read ↗

TNFSF4 Gene Variations Are Related to Early-Onset Autoimmune Thyroid Diseases and Hypothyroidism of Hashimoto's Thyroiditis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.