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Article

CD146 attenuation in cancer‐associated fibroblasts promotes pancreatic cancer progression

16 Sept 2015

Abstract excerpt

Cancer-associated fibroblasts (CAFs) are heterogeneous cell populations that influence tumor initiation and progression. CD146 is a cell membrane protein whose expression has been implicated in multiple human cancers. CD146 expression is also detected in pancreatic cancer stroma; however, the role it plays in this context remains unclear. This study aimed to clarify the function and significance of CD146...

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PMID: 26373617
DOI: 10.1002/mc.22409

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