Article
Podoplanin, α-smooth muscle actin or S100A4 expressing cancer-associated fibroblasts are associated with different prognosis in colorectal cancers.
Journal of Korean medical science - 1 Sept 2013
Choi Song-Yi, Sung Rohyun, Lee Sang-Jeon, Lee Taek-Gu, Kim Nayoung, Yoon Soon Man, Lee Eun Jeoung, Chae Hee Bok, Youn Sei Jin, Park Seon Mee
Abstract excerpt
The interactions between the tumor microenvironment and tumor cells determine the behavior of the primary tumors. Whether cancer-associated fibroblasts (CAF) have a tumor progressive or a protective role likely depends on the type of tumor cells and the CAF subpopulation. In the present study, we analyzed the prognostic significance of CAF subpopulations in colorectal cancer (CRC). CAF phenotypes were analyzed in...
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