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Gene expression profile in the activation of subperitoneal fibroblasts reflects prognosis of patients with colon cancer

15 Sept 2015

Abstract excerpt

Tumors can create a heterogenetic tumor microenvironment. We recently identified the pathologically unique cancer microenvironment formed by peritoneal invasion (CMPI), and revealed that subperitoneal fibroblasts (SPFs) within peritoneal tissue play a crucial role in tumor progression through their interaction with cancer cells. Therefore, the genes in SPFs altered by cancer stimulation may include some...

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PMID: 26370611
DOI: 10.1002/ijc.29851

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