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Identification and validation of an immune-related gene signature predictive of overall survival in colon cancer

19 Dec 2020

Abstract excerpt

The heterogeneity and complexity of tumor-immune microenvironments lead to diverse immunotherapy effects among colon cancer patients. It is crucial to identify immune microenvironment-related biomarkers and construct prognostic risk models. In this study, the immune and stromal scores of 415 cases from TCGA were calculated using the ESTIMATE algorithm. AXIN2, CCL22, CLEC10A, CRIP2, RUNX3, and TRPM5 were screened...

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Cancer Immunotherapy and Biomarkers
Ferroptosis and cancer prognosis
Genetic factors in colorectal cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33401247
DOI: 10.18632/aging.202317

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