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Article

Genotypic Analysis of Genes Associated with Independent Resistance and Cross-Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis Clinical Isolates.

Antimicrobial agents and chemotherapy - 1 Dec 2015

Rueda Johana, Realpe Teresa, Mejia Gloria Isabel, Zapata Elsa, Rozo Juan Carlos, Ferro Beatriz Eugenia, Robledo Jaime

Abstract excerpt

Ethionamide (ETH) is an antibiotic used for the treatment of multidrug-resistant (MDR) tuberculosis (TB) (MDR-TB), and its use may be limited with the emergence of resistance in the Mycobacterium tuberculosis population. ETH resistance in M. tuberculosis is phenomenon independent or cross related when accompanied with isoniazid (INH) resistance. In most cases, resistance to INH and ETH is explained by mutations...

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Identifiers

PMID: 26369965
DOI: 10.1128/AAC.01028-15
PMCID: PMC4649173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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