Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations.

The Journal of antimicrobial chemotherapy - 1 Aug 2013

Machado Diana, Perdigão João, Ramos Jorge, Couto Isabel, Portugal Isabel, Ritter Claudia, Boettger Erik C, Viveiros Miguel

Abstract excerpt

OBJECTIVES: The purpose of this study was to determine the levels of isoniazid and ethionamide resistance and to identify associated mutations in endemic multidrug-resistant (MDR) strains of Mycobacterium tuberculosis from the Lisbon metropolitan area, Portugal. METHODS: Seventeen clinical MDR tuberculosis (TB) strains were characterized by standard and semi-quantitative drug susceptibility testing to assess the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Drug Resistance, Multiple, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Isoniazid

Share to Molecular Typing

Share to Mycobacterium tuberculosis

Share to Oxidoreductases

Share to Portugal

Share to Tuberculosis, Multidrug-Resistant

Source

Identifiers

PMID: 23539241
DOI: 10.1093/jac/dkt090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations.PMID 23539241Read ↗

Multidrug-resistant tuberculosis in Lisbon, Portugal: a molecular epidemiological perspective.Semantic proximity Read ↗

Isoniazid-resistant tuberculosis: a cause for concern?Semantic proximity Read ↗

Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities.Semantic proximity Read ↗

From multidrug-resistant to extensively drug-resistant tuberculosis in Lisbon, Portugal: the stepwise mode of resistance acquisition.Semantic proximity Read ↗

Mycobacterial interspersed repetitive unit typing and mutational profile for multidrug-resistant and extensively drug-resistant tuberculosis surveillance in Portugal: a 3-year period overview.Semantic proximity Read ↗

Genetic mutations associated with isoniazid resistance in Mycobacterium tuberculosis: a systematic review.Semantic proximity Read ↗

Tuberculosis drug-resistance in Lisbon, Portugal: a 6-year overview.Semantic proximity Read ↗

Genetic diversity of Mycobacterium tuberculosis isoniazid monoresistant and multidrug-resistant in Rio Grande do Sul, a tuberculosis high-burden state in Brazil.Semantic proximity Read ↗

Genetic analysis of extensively drug-resistant Mycobacterium tuberculosis strains in Lisbon, Portugal.Semantic proximity Read ↗

Detection and characterization of mutations in genes related to isoniazid resistance in Mycobacterium tuberculosis clinical isolates from Iran.Semantic proximity Read ↗

Ethionamide cross- and co-resistance in children with isoniazid-resistant tuberculosis.Semantic proximity Read ↗

Genotypic analysis of Mycobacterium tuberculosis isolates from a Lisbon hospital in Portugal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.