Article
Pan-cancer integrative analysis of whole-genome De novo somatic point mutations reveals 17 cancer types.
BMC bioinformatics - 25 Jul 2022
Ghareyazi Amin, Kazemi Amirreza, Hamidieh Kimia, Dashti Hamed, Tahaei Maedeh Sadat, Rabiee Hamid R, Alinejad-Rokny Hamid, Dehzangi Iman
Abstract excerpt
BACKGROUND: The advent of high throughput sequencing has enabled researchers to systematically evaluate the genetic variations in cancer, identifying many cancer-associated genes. Although cancers in the same tissue are widely categorized in the same group, they demonstrate many differences concerning their mutational profiles. Hence, there is no definitive treatment for most cancer types. This reveals the...
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