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Histone Deacetylase Gene Expression Following Binge Alcohol Consumption in Rats and Humans

13 Sept 2015

Abstract excerpt

BACKGROUND: Alcohol binge drinking is one of the most common patterns of excessive alcohol use and recent data would suggest that histone deacetylases (HDACs) gene expression profiling could be useful as a biomarker for psychiatric disorders. METHODS: This study aimed to characterize the gene expression patterns of Hdac 1-11 in samples of rat peripheral blood, liver, heart, prefrontal cortex, and amygdala...

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PMID: 26365275
DOI: 10.1111/acer.12850

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