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Article

Mechanisms of neuroimmune gene induction in alcoholism

19 Mar 2015

Abstract excerpt

RATIONALE: Alcoholism is a primary, chronic relapsing disease of brain reward, motivation, memory, and related circuitry. It is characterized by an individual's continued drinking despite negative consequences related to alcohol use, which is exemplified by alcohol use leading to clinically significant impairment or distress. Chronic alcohol consumption increases the expression of innate immune signaling...

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PMID: 25787746
DOI: 10.1007/s00213-015-3906-1

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