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Article

Epigenetic basis of the dark side of alcohol addiction.

Neuropharmacology - 1 Aug 2017

Pandey Subhash C, Kyzar Evan J, Zhang Huaibo

Abstract excerpt

Alcoholism is a complex brain disease characterized by three distinct stages of the addiction cycle that manifest as neuroadaptive changes in the brain. One such stage of the addiction cycle is alcohol withdrawal and the negative affective states that promote drinking and maintain addiction. Repeated alcohol use, genetic predisposition to alcoholism and anxiety, and alcohol exposure during crucial developmental...

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Source

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Identifiers

PMID: 28174112
DOI: 10.1016/j.neuropharm.2017.02.002
PMCID: PMC5479721

Genes

HDAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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