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Histone deacetylases inhibitor trichostatin A reverses anxiety-like symptoms and memory impairments induced by maternal binge alcohol drinking in mice

11 Jul 2019

Abstract excerpt

BACKGROUND: Alcohol exposure during development has detrimental effects, including a wide range of physical, cognitive and neurobehavioural anomalies known as foetal alcohol spectrum disorders. However, alcohol consumption among pregnant woman is an ongoing latent health problem. AIM: In the present study, the effects of trichostatin A (TSA) on emotional and cognitive impairments caused by prenatal and...

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PMID: 31294671
DOI: 10.1177/0269881119857208

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