Article
Interaction between common breast cancer susceptibility variants, genetic ancestry, and nongenetic risk factors in Hispanic women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2015
Fejerman Laura, Stern Mariana C, John Esther M, Torres-Mejía Gabriela, Hines Lisa M, Wolff Roger K, Baumgartner Kathy B, Giuliano Anna R, Ziv Elad, Pérez-Stable Eliseo J, Slattery Martha L
Abstract excerpt
BACKGROUND: Most genetic variants associated with breast cancer risk have been discovered in women of European ancestry, and only a few genome-wide association studies (GWAS) have been conducted in minority groups. This research disparity persists in post-GWAS gene-environment interaction analyses. We tested the interaction between hormonal and lifestyle risk factors for breast cancer, and ten GWAS-identified...
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