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Genetic variation in genes involved in hormones, inflammation and energetic factors and breast cancer risk in an admixed population.

Carcinogenesis - 1 Aug 2012

Slattery Martha L, John Esther M, Torres-Mejia Gabriela, Lundgreen Abbie, Herrick Jennifer S, Baumgartner Kathy B, Hines Lisa M, Stern Mariana C, Wolff Roger K

Abstract excerpt

Breast cancer incidence rates are characterized by unique racial and ethnic differences. Native American ancestry has been associated with reduced breast cancer risk. We explore the biological basis of disparities in breast cancer risk in Hispanic and non-Hispanic white women by evaluating genetic variation in genes involved in inflammation, insulin and energy homeostasis in conjunction with genetic ancestry....

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Source

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Identifiers

PMID: 22562547
DOI: 10.1093/carcin/bgs163
PMCID: PMC3499059

Genes

PTEN
PDK2
PRKAA1
STK11
TSC1

Provenance

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